Excerpt: British scientists claim to have made a massive step towards creating new treatments to beat cancer.

Experts created a "working" model of a key cancer protein - and believe it has a flaw which means it can be "switched off".

The protein kinase B (PKB) is seen in many tumours and the model revealed it has a hidden cavity which controls its activity.

By turning off this part, they would be able to stop it becoming overactive, which can be a factor in creating tumours.

Until now, there have been no ways of turning off the over-active part of the enzyme which are safe for humans.

Professor Banafshe Larijani, from Cancer Research UK's Bell Biophysics Laboratory, said: "An overactive form of PKB is...